Cold Rooms Built for Critical Storage and Protection
Cold Rooms and Warehousing
CleanSpace designs and builds temperature-controlled environments where environmental consistency and product protection are critical. Our modern design build approach integrates planning, engineering, manufacturing, construction, commissioning, and operational readiness into one coordinated delivery model, reducing project risk while accelerating deployment for cold storage infrastructure.
From refrigerated storage and controlled environments to biologic material preservation and ultra-low temperature applications, our teams engineer cold rooms around process requirements, operational workflows, temperature recovery performance, and long-term reliability. We understand the critical relationship between refrigeration systems, insulation assemblies, airflow, vapor barriers, humidity control, door openings, and environmental monitoring, ensuring facilities maintain stable operating conditions under real world production demands.
CleanSpace delivers scalable temperature-controlled clean room environments supporting a wide range of operating conditions, including refrigerated warehouses and storage, freezer applications, and ultra-low temperature spaces reaching as low as -80 degrees Celsius. Our teams also provide temperature mapping, commissioning, airflow analysis, calibration coordination, and qualification readiness to help clients achieve compliant and operationally reliable environments.
Our certifications
Turnkey Cold Room Design, Manufacturing, and Installation
From 2 to 8 °C vaccine and biologic storage to -20 °C, -40 °C, and ultra-low -80 °C environments, CleanSpace is a single-source modular cold room manufacturer and builder. We design, fabricate in our US facility, and install on your site, removing vendor hand-offs, supply-chain delays, and cost overruns.
Design And Engineering
CleanSpace designs and engineers temperature controlled environments built for seamless integration, reliable performance, and long-term environmental stability.
Precision Temperature and Humidity Control
Redundant cooling systems, validated controls, and continuous monitoring engineered to hold setpoint under real-world load.
Design Build
Our Design Build Process compresses the schedule from design through IQ/OQ validation. Turnkey installation by CleanSpace crews means one accountable partner from concept to qualified handoff.
Across all engagements, CleanSpace has distinguished themselves as a highly reliable,knowledgeable, and adaptable partner. Their professionalism, technical competence, andcommitment to delivering compliant, high‑quality environments make them an asset to anyorganization operating within regulated pharmaceutical or sterile manufacturing settings.
Cold Room Applications
Every cold environment is engineered to the exact setpoint, tolerance, and regulatory standard your process requires. CleanSpace regularly designs and builds:
Controlled Temperature Storage
Temperature controlled environments supporting pharmaceutical materials, biologics, injectables, finished goods, and regulated storage operations.
Biologics and Vaccine Environments
Cold storage infrastructure designed for biologics preservation, vaccine storage, temperature sensitive therapeutics, and cGMP regulated support spaces.
Ultra Low Temperature Applications
High performance freezer environments supporting biologic materials, drug substance storage, and specialized low temperature process requirements.
Environmental Monitoring and Temperature Mapping
Integrated monitoring strategies supporting calibrated sensor placement, temperature uniformity analysis, recovery verification, and qualification driven performance documentation.
Process Driven Infrastructure
Cold room systems engineered around airflow performance, humidity control, vapor barriers, airlocks, insulated assemblies, equipment loads, and operational workflows to ensure long term reliability and product protection.
Integrated Delivery and Operational Readiness
End to end project execution including preconstruction planning, engineering coordination, modular system manufacturing, installation, commissioning, startup support, and qualification readiness for regulated operations.
Clean spaces for a variety of industries
Integrated Cold Storage for cGMP Operations
Temperature controlled environments are often a critical component within larger cGMP manufacturing and regulated production facilities. CleanSpace understands how cold rooms, refrigerated process spaces, biologics storage, warehouses, and ultra-low temperature environments must integrate seamlessly with cleanrooms, aseptic processing suites, manufacturing workflows, material flow strategies, and validated GMP operations.
Our teams bring expertise in both controlled environment construction and temperature controlled infrastructure, allowing us to design and deliver cohesive facilities that align refrigeration systems, environmental controls, cleanroom performance, utility coordination, and operational requirements under one integrated design build approach. This coordination reduces risk, improves system reliability, and ensures critical environments operate together as part of a unified manufacturing ecosystem.
In addition to design and construction, CleanSpace supports long term operational performance through commissioning coordination, temperature mapping, environmental verification, ongoing service support, and maintenance programs. From initial planning through sustained operations, we help clients maintain reliable, compliant, and high performing environments built around the demands of modern cGMP manufacturing.
Where We Work
CleanSpace delivers projects throughout the United States, Canada, and select markets in Central and South America. Our reach spans major life sciences, pharmaceutical, healthcare and advanced manufacturing regions, supporting clients wherever controlled environment facilities are needed. In the United States, we serve key industry hubs coast to coast.
Corporate Headquarters
CleanSpace Modular, LLC1035 Virginia Drive, Suite 301 | Fort Washington, PA 19034
Manufacturing and Warehouse Facility
4350 W White Road, Suite 100 Oakwood, GA 30566
Michigan Corporate Office | CleanShield
2424 Wolcott StreetFerndale, MI 48220
Houston Corporate Office
6977 Wynnwood LaneHouston, TX 77008
Dallas Corporate Office
3020 Pegasus Park DriveDallas, TX 75247
Case Studies
The Modern Design Build Process
Our team accelerates the design to installation process and is what enables CleanSpace to offer timeline and budget guarantees.
CleanSpace Insights
Improve the speed and efficiency, provoke dialogue for alignment and consider key decision points as you prepare for your next project.
Cold Room FAQs
What is a modular cold room?
A modular cold room is a prefabricated, insulated, temperature-controlled environment built from engineered panel systems. Unlike stick-built cold storage, modular cold rooms install faster, can be reconfigured as processes change, and deliver consistent GMP and HACCP performance.
What temperature ranges does CleanSpace design to?
We routinely design and build controlled room temperature (15 to 25 °C), refrigerated (2 to 8 °C), frozen (minus 20 and minus 40 °C), and ultra-low (minus 80 °C) environments, along with ICH-compliant stability chambers.
Are CleanSpace cold rooms GMP and HACCP compliant?
Yes. Every cold room is engineered to meet GMP, HACCP, FDA, and applicable EU requirements, with documentation to support IQ, OQ, and PQ validation.
Do you build stability chambers?
Yes. CleanSpace designs and installs ICH Q1A compliant stability chambers at standard setpoints (25 °C / 60% RH, 30 °C / 65% RH, 40 °C / 75% RH) and custom profiles for pharmaceutical stability testing.
Do you serve clients nationwide?
Yes. CleanSpace serves clients across the United States with US-based manufacturing and self-performed installation crews supporting every major life sciences, healthcare, and food and beverage region.
How long does it take to build a modular cold room?
CleanFit® typically delivers a modular cold room or stability chamber in a fraction of the time of conventional construction, moving from design to validated handoff in weeks rather than many months.
How much does a cold room cost?
Cost depends on temperature range, square footage, redundancy, monitoring, and equipment integration. CleanFit® provides a fixed-price, guaranteed-timeline quote after a scoping session.